56776-01-3 Tulobuterol HCl AKSci J10478
 
 
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  J10478    AKSci Reference Standard
Tulobuterol HCl
, 99% (HPLC), powder
 
2-tert-Butylamino-1-(2-chlorophenyl)ethanol hydrochloride




IDENTITY
CAS Number:56776-01-3
MDL Number:MFCD00214398
MF:C12H19Cl2NO
MW:264.19
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:159-164°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Form:HCl salt

REVIEW

 Tulobuterol is a long-acting beta2-adrenergic receptor agonist,which acts as a bronchodilator, marketed in Japan as a transdermal patch under the name Hokunalin tape. This is the first bronchodilator to be available as a transdermal patch, and isused in the treatment of chronic obstructive lung disease.

REFERENCES
[1]Kubo, S.; Kase, Y.; Miyata, T.; Kito, G.; Uesaka, I. Pharmacological studies of 1-(o-chlorophenyl)-2-tert-butylaminoethanol (C-78), a new bronchodilator. Arzneimittel-Forschung (1975), 25(7), 1028-37.
[2] Bogan, J. A. Tulobuterol hydrochloride. Drugs of Today (1982), 18(5), 238-43.
[3] Patel KR. Tulobuterol in the management of obstructive airways disease in adults. Clin Ther. 1985;7(4):452-67.
[4] Kato H, Nagata O, Yamazaki M, Suzuki T, Nakano Y. Yakugaku Zasshi. Development of transdermal formulation of tulobuterol for the treatment of bronchial asthma. 2002 Jan;122(1):57-69.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P264; P270; P301+P312; P330; P501


Current as of October 2, 2022

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Adrenergic Agonists


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