REVIEW Tulobuterol is a long-acting beta2-adrenergic receptor agonist,which acts as a bronchodilator, marketed in Japan as a transdermal patch under the name Hokunalin tape. This is the first bronchodilator to be available as a transdermal patch, and isused in the treatment of chronic obstructive lung disease.
REFERENCES
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Kubo, S.; Kase, Y.; Miyata, T.; Kito, G.; Uesaka, I. Pharmacological studies of 1-(o-chlorophenyl)-2-tert-butylaminoethanol (C-78), a new bronchodilator. Arzneimittel-Forschung (1975), 25(7), 1028-37.
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Bogan, J. A. Tulobuterol hydrochloride. Drugs of Today (1982), 18(5), 238-43.
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Patel KR. Tulobuterol in the management of obstructive airways disease in adults. Clin Ther. 1985;7(4):452-67.
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Kato H, Nagata O, Yamazaki M, Suzuki T, Nakano Y. Yakugaku Zasshi. Development of transdermal formulation of tulobuterol for the treatment of bronchial asthma. 2002 Jan;122(1):57-69.
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