59-92-7 L-DOPA AKSci J10404
 
 
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  J10404    AKSci Reference Standard
L-DOPA, 99% (HPLC)
 
Levodopa
3,4-Dihydroxy-L-phenylalanine
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IDENTITY
CAS Number:59-92-7
MDL Number:MFCD00002598
MF:C9H11NO4
MW:197.19
EINECS:200-445-2
BRN:2215169
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:270-280°C
Optical Rotation:-11.7° (c=5.3, 1N HCl)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:H2O: 66mg/mL; EtOH: insoluble; 0.5M HCl: 50mg/mL
Application(s):Antiparkinson Agent; Dopamine Agent
Form:Free Base

REVIEW
 L-DOPA is the precursor to the neurotransmitters dopamine, norepinephrine (noradrenaline), and epinephrine (adrenaline) collectively known as catecholamines.

REFERENCES
[1]Quik M, Park KM, Hrachova M, Mallela A, Huang LZ, McIntosh JM, Grady SR (2012). Role for alpha6 nicotinic receptors in l-dopa-induced dyskinesias in parkinsonian mice. Neuropharmacology. 63(3):450-9. PMID 22579614.
[2] Golembiowska K, Dziubina A (2012). The effect of adenosine A(2A) receptor antagonists on hydroxyl radical, dopamine, and glutamate in the striatum of rats with altered function of VMAT2. Neurotox Res. 22(2):150-7. PMID 22407500.
[3] Yoon, Seung-Heon; Carbohydrate Research 2009, V344(17), P2349-2356

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H315; H319; H335

Precautionary Statements
P261; P264; P270; P271; P280; P301+P312; P302+P352; P304+P340; P305+P351+P338; P312; P321; P330; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of March 25, 2023

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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⚠️
These chemical products are for research and development use only. They are not for diagnostic, therapeutic, cosmetic, or human and animal uses. They are not sold to individuals. Additional restrictions may apply.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information.
⚠️

WARNING: Attention California residents: This product can expose you to chemicals including L-DOPA, which is known to the State of California to cause birth defects or other reproductive harm. For more information, go to www.P65Warnings.ca.gov.




CATEGORIES
 Amino Acids > Phenylalanine


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