146-78-1 2-Fluoroadenosine AKSci J10354
 
 
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  J10354    AKSci Reference Standard
2-Fluoroadenosine, >98% (HPLC)
 



IDENTITY
CAS Number:146-78-1
MDL Number:MFCD00866394
MF:C10H12FN5O4
MW:285.23
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:222-228°C
Optical Rotation:-67 ~ -61° (c=1, DMSO)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):A cell permeable agent that interferes with DNA synthesis and repair; also inhibits RNA transcriptio

REVIEW
 Fludarabine is a prodrug converted to free nucleoside 9-beta-D-arabinosyl-2-fluoroadenine (F-ara-A). F-ara-A enters cells and accumulates as 5'-triphosphate. Interferes with DNA synthesis and repair. Induces apoptosis of cancer cells and RNA transcription inhibitor.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H315; H319; H335

Precautionary Statements
P261; P264; P270; P271; P280; P301+P312; P302+P352; P304+P340; P305+P351+P338; P312; P321; P330; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of June 30, 2022

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES
 Nucleobases > Nucleosides


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