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REVIEW Tegafur is a chemotherapeutic fluorouracil prodrug used in the treatment of cancers. It is a component of the combination drug tegafur-uracil. When metabolized, it becomes 5-fluorouracil.
REFERENCES
[1]
El Sayed, YM; Sadée, W (1983). Metabolic activation of R,S-1-(tetrahydro-2-furanyl)-5-fluorouracil (ftorafur) to 5-fluorouracil by soluble enzymes. Cancer Research 43 (9): 4039-44. PMID 6409396.
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