REVIEW L-Thyroxine is a synthetically prepared levo isomer of thyroxine, the major hormone secreted from the thyroid gland and it acts like the endogenous thyroid hormone thyroxine (T4, a tetra-iodinated tyrosine derivative). L-Thyroxine is used alone or in combination with antithyroid agents to treat hypothyroidism, goiter, chronic lymphocytic thyroiditis, myxedema coma, and stupor.
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'Salamonczyk, Grzegorz M.; Oza, Vibha B.; Sih, Charles J.A concise synthesis of thyroxine (T4) and 3,5,3''-triiodo-L-thyronine (T3) Tetrahedron Letters (1997), 38(40), 6965-6968.'
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