REVIEW L-Thyroxine is a synthetically prepared levo isomer of thyroxine, the major hormone secreted from the thyroid gland and it acts like the endogenous thyroid hormone thyroxine (T4, a tetra-iodinated tyrosine derivative). L-Thyroxine is used alone or in combination with antithyroid agents to treat hypothyroidism, goiter, chronic lymphocytic thyroiditis, myxedema coma, and stupor.
Koch L. Pharmacotherapy: Levothyroxine in the elderly-finding the breaking point. Nat Rev Endocrinol. (2011) Jun 14;7(8): 435.
Andrade C. Levothyroxine in psychiatry: issues related to absorption after oral dosing. J Clin Psychiatry. (2013) Aug;74(8): e744-6.
De Vito P, Incerpi S, Pedersen JZ, Luly P, Davis FB, Davis PJ. Thyroid hormones as modulators of immune activities at the cellular level. Thyroid. (2011) Aug;21(8): 879-90.
'Salamonczyk, Grzegorz M.; Oza, Vibha B.; Sih, Charles J.A concise synthesis of thyroxine (T4) and 3,5,3''-triiodo-L-thyronine (T3) Tetrahedron Letters (1997), 38(40), 6965-6968.'
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