93-14-1 Guaifenesinum AKSci J10304
 
 
Loading Please Wait...
  J10304    AKSci Reference Standard
Guaifenesinum
, >99% (GC)
 
Guaiphenesin
Guaiacol glyceryl ether
Glycerol guaiacolate
more..




IDENTITY
CAS Number:93-14-1
MDL Number:MFCD00016873
MF:C10H14O4
MW:198.22
EINECS:202-222-5
BRN:2049375
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>99% (GC)
Physical Form (at 20°C):Solid
Melting Point:82-85°C
Boiling Point:215°C (19mmHg)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 40mg/mL; H2O: 25mg/mL; EtOH: 40mg/mL
Application(s):Expectorant
Form:Free Base

REVIEW

 Guaifenesin is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. It also stimulates the flow of respiratory tract secretions, allowing ciliary movement to carry the loosened secretions upward toward the pharynx.

REFERENCES
[1]Hu Z, Zou Q, Tian J, Sun L, Zhang Z (2011). Simultaneous determination of codeine, ephedrine, guaiphenesin and chlorpheniramine in beagle dog plasma using high performance liquid chromatography coupled with tandem mass spectrometric detection: application to a bioequivalence study. J Chromatogr B Analyt Technol Biomed Life Sci. 879(32):3937-42. PMID 22119507.
[2] Seagrave J, Albrecht H, Park YS, Rubin B, Solomon G, Kim KC (2011). Effect of guaifenesin on mucin production, rheology, and mucociliary transport in differentiated human airway epithelial cells. Exp Lung Res. 37(10):606-14. PMID 22044398.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302; H315; H319; H335

Precautionary Statements
P261; P264; P270; P271; P280; P301+P312; P302+P352; P304+P340; P305+P351+P338; P312; P321; P330; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of October 2, 2022

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS Request COA

⚠️
These chemical products are for research and development use only. They are not for diagnostic, therapeutic, cosmetic, or human and animal uses. They are not sold to individuals. Additional restrictions may apply.
New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information.


CATEGORIES

 APIs and Bioactives > Mucokinetics


PubChem