297-76-7 Ethynodiol diacetate AKSci J10286
 
 
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  J10286    AKSci Reference Standard
Ethynodiol diacetate
, >98% (HPLC)
 
3beta,17beta-Diacetoxy-17a-ethynyl-4-estrene




IDENTITY
CAS Number:297-76-7
MDL Number:MFCD00083326
MF:C24H32O4
MW:384.51
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:126-127°C
Optical Rotation:-72.5° (Chloroform)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 Ethynodiol diacetate is a synthetic progestational hormone, a synthetic form of the naturally occurring female sex hormone. It tricks the body processes into thinking that ovulation has already occurred, by maintaining high levels of the synthetic progesterone. Ethynodiol diacetate binds to the progesterone and estrogen receptors. Once bound to the receptor, it will slow the frequency of release of gonadotropin releasing hormone from the hypothalamus and blunt the pre-ovulatory LH (luteinizing hormone) surge.

REFERENCES
[1]Orme ML, Back DJ, Breckenridge AM. Clinical pharmacokinetics of oral contraceptive steroids. Clin Pharmacokinet. (1983) Mar-Apr;8(2): 95-136.
[2] Ellis J. Low-dose oral contraceptives: progestin potency, androgenicity, and atherogenic potential. Clin Ther. (1986) 8(6): 607-18.
[3] Mishell D R Jr. Current status of contraceptive steroids and the intrauterine device. Clinical Obstetrics and Gynecology. (1974) 17(1): 35-51.
[4] 3,17beta-Diacetoxy-17alpha-ethynylestr-4-ene (1963), FR M2070 19631112.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302+H312+H332; H351

Precautionary Statements
P201; P202; P261; P264; P270; P271; P280; P301+P312; P302+P352; P304+P340; P308+P313; P322; P330; P363; P405; P501


Current as of January 31, 2025

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Steroid Hormones


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