126-07-8 (+)-Griseofulvin AKSci J10209
 
 
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  J10209    AKSci Reference Standard
(+)-Griseofulvin
, 98% (HPLC)
 



IDENTITY
CAS Number:126-07-8
MDL Number:MFCD00082343
MF:C17H17ClO6
MW:352.77
EINECS:204-767-4
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Spectra:FT-IR, LCMS, HPLC, Polarimetry
Physical Form:White to off-white powder
Melting Point:217-224°C
Optical Rotation:354° (c=1, DMF)
Long-Term Storage:Store long-term at -20°C
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

REVIEW

 Griseofulvin is fungistatic, however the exact mechanism by which it inhibits the growth of dermatophytes is not clear. It is thought to inhibit fungal cell mitosis and nuclear acid synthesis. It also binds to and interferes with the function of spindle and cytoplasmic microtubules by binding to alpha and beta tubulin. It binds to keratin in human cells, then once it reaches the fungal site of action, it binds to fungal microtubes thus altering the fungal process of mitosis.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H317; H351; H360

Precautionary Statements
P201; P202; P261; P272; P280; P302+P352; P308+P313; P321; P333+P313; P363; P405; P501


Current as of April 19, 2021

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.

WARNING: Attention California residents: This product can expose you to chemicals including (+)-Griseofulvin, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.


CATEGORIES

 APIs and Bioactives > Fungicides


PubChem