REVIEW Griseofulvin is fungistatic, however the exact mechanism by which it inhibits the growth of dermatophytes is not clear. It is thought to inhibit fungal cell mitosis and nuclear acid synthesis. It also binds to and interferes with the function of spindle and cytoplasmic microtubules by binding to alpha and beta tubulin. It binds to keratin in human cells, then once it reaches the fungal site of action, it binds to fungal microtubes thus altering the fungal process of mitosis.
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WARNING: Attention California residents: This product can expose you to chemicals including (+)-Griseofulvin, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.