REVIEW An antineoplastic chemotherapy drug used in the treatment of various cancers. Dacarbazine is a member of the class of alkylating agents that destroy cancer cells by adding an alkyl group (CnH2n+1) to its DNA.
REFERENCES
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Margolin K (2012). BRAF inhibition and beyond in advanced melanoma. Lancet. 380(9839):320-2. PMID 22735383.
[2]
Hauschild A, Grob JJ, Demidov LV, Jouary T, Gutzmer R, Millward M, Rutkowski P, Blank CU, Miller WH Jr, Kaempgen E, Martín-Algarra S, Karaszewska B, Mauch C, Chiarion-Sileni V, Martin AM, Swann S, Haney P, Mirakhur B, Guckert ME, Goodman V, Chapman PB (2012). Dabrafenib in BRAF-mutated metastatic melanoma: a multicentre, open-label, phase 3 randomised controlled trial. Lancet. 2012 Jul 28;380(9839):358-65. PMID 22735384.
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WARNING: Attention California residents: This product can expose you to chemicals including Dacarbazine, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.
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