3902-71-4 Trioxsalen AKSci J10195
 
 
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  J10195    AKSci Reference Standard
Trioxsalen
, 99% (HPLC), powder
 
2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one
4,5',8-Trimethylpsoralen
TMP
more..




IDENTITY
CAS Number:3902-71-4
MDL Number:MFCD00005010
MF:C14H12O3
MW:228.24
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Spectra:NMR, LCMS, HPLC
Physical Form:White to off-white to light yellow crystal or powder
Melting Point:229-238°C
Long-Term Storage:Store long-term at -20°C
HAZARDOUS MATERIALS INFORMATION
UN #:UN1759
Hazard Class:8; Corrosive
Packing Group:II
A hazmat fee may apply, depending on the amount ordered.

REVIEW

 After photoactivation it creates interstrand cross-links in DNA, which can cause programmed cell death.

REFERENCES
[1]van Coevorden AM, Kamphof WG, van Sonderen E, Bruynzeel DP, Coenraads PJ: Comparison of oral psoralen-UV-A with a portable tanning unit at home vs hospital-administered bath psoralen-UV-A in patients with chronic hand eczema: an open-label randomized controlled trial of efficacy. Arch Dermatol. 2004 Dec;140(12):1463-6.
[2] Thazhathveetil AK, Liu ST, Indig FE, Seidman MM: Psoralen conjugates for visualization of genomic interstrand cross-links localized by laser photoactivation. Bioconjug Chem. 2007 Mar-Apr;18(2):431-7.
[3] Higuchi M, Yamayoshi A, Kobori A, Yamaoka T, Murakami A: Synthesis and properties of photo-reactive antisense oligonucleotides containing 2'-O-psoralen-conjugated adenosine. Nucleic Acids Symp Ser (Oxf). 2005;(49):331-2.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H314; H351

Precautionary Statements
P201; P202; P260; P264; P280; P301+P330+P331; P303+P361+P353; P304+P340; P305+P351+P338; P310; P321; P363; P405; P501


Current as of June 16, 2021

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Natural Products, Dermatology


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