1400645-02-4 Ofloxacin Hydrochloride AKSci J10174
 
 
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  J10174    AKSci Reference Standard
Ofloxacin Hydrochloride, 99% (HPLC)
 



IDENTITY
CAS Number:1400645-02-4
MDL Number:MFCD06410951
MF:C18H21ClFN3O4
MW:397.83
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Antibiotic; Antimicrobial Agent; Nucleic Acid Synthesis Inhibitor
Form:HCl salt

REVIEW
 Ofloxacin acts on DNA gyrase and toposiomerase IV, enzymes which, like human topoisomerase, prevents the excessive supercoiling of DNA during replication or transcription. By inhibiting their function, the drug thereby inhibits normal cell division.

REFERENCES
[1]Kawahara, S. (December 1998). [Chemotherapeutic agents under study]. Nippon Rinsho 56 (12): 3096-9. PMID 9883617.
[2] Nelson, JM.; Chiller, TM.; Powers, JH.; Angulo, FJ. (Apr 2007). Fluoroquinolone-resistant Campylobacter species and the withdrawal of fluoroquinolones from use in poultry: a public health success story. Clin Infect Dis 44 (7): 977-80. doi:10.1086/512369. PMID 17342653.
[3] Davis, R.; Bryson, H. M. (1994). Levofloxacin. Drugs 47 (4): 677-700. doi:10.2165/00003495-199447040-00008. PMID 7516863.
[4] Blum, A (1991). Ofloxacin-induced acute severe hepatitis. Southern Medical Journal 84 (9): 1158. doi:10.1097/00007611-199109000-00027. PMID 1891746.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of September 22, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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