83881-52-1 Cetirizine dihydrochloride AKSci J10151
 
 
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  J10151    AKSci Reference Standard
Cetirizine dihydrochloride, >99% (HPLC), powder
 
Cetirizine
Reactine
Zyrtec
more..
IDENTITY
CAS Number:83881-52-1
MDL Number:MFCD00941428
MF:C21H27Cl3N2O3
MW:461.81
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:217-225°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 92mg/mL; H2O: >10mg/mL; EtOH: <1mg/mL
Application(s):Selective H1-receptor antagonist
Form:HCl salt

REVIEW
 An antihistamine. It is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria.

REFERENCES
[1]Espay AJ (2008). Reversible parkinsonism and ataxia associated with high-dose octreotide. Neurology. 70(24):2345-6. PMID 18463367.
[2] Jones MC, Jones CE 2nd (2010). Use of cetirizine in a 23-month-old male causes insomnia. South Med J. 103(5):485-6. PMID 20375960.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H302

Precautionary Statements
P264; P270; P301+P312; P330; P501

Current as of February 3, 2025

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES
 APIs and Bioactives > Antihistamines


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