139264-17-8 Zolmitriptan AKSci J10141
 
 
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  J10141    AKSci Reference Standard
Zolmitriptan
, >98% (HPLC), powder
 
(4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone
(S)-4-((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)-2-oxazolidinone
Zomig
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IDENTITY
CAS Number:139264-17-8
MDL Number:MFCD00871503
MF:C16H21N3O2
MW:287.36
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:136-141°C
Optical Rotation:-3° to -9° (c=1, MeOH)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 5mg/mL; H2O: <1mg/mL; EtOH: 58mg/mL
Application(s):Selective 5-hydroxytryptamine 1B/1D (5-HT1B/1D) receptor agonist
Form:Free Base

REVIEW

 A selective serotonin receptor agonist of the 1B and 1D subtypes.

REFERENCES
[1]Dalpiaz A, Marchetti N, Cavazzini A, Pasti L, Velaga S, Gavini E, Beggiato S, Ferraro L (2012). Quantitative determination of zolmitriptan in rat blood and cerebrospinal fluid by reversed phase HPLC-ESI-MS/MS analysis: application to in vivo preclinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 901:72-8. PMID 22743338.
[2] Lionetto L, Casolla B, Mastropietri F, D'Alonzo L, Negro A, Simmaco M, Martelletti P (2012). Pharmacokinetic evaluation of zolmitriptan for the treatment of migraines. Expert Opin Drug Metab Toxicol. 8(8):1043-50. PMID 22762358.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of June 25, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Serotonin Agonists


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