139264-17-8 Zolmitriptan AKSci J10141
 
 
Loading Please Wait...
  J10141    AKSci Reference Standard
Zolmitriptan, >98% (HPLC), powder
 
(4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone
(S)-4-((3-(2-(Dimethylamino)ethyl)indol-5-yl)methyl)-2-oxazolidinone
Zomig
more..
IDENTITY
CAS Number:139264-17-8
MDL Number:MFCD00871503
MF:C16H21N3O2
MW:287.36
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:>98% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:136-141°C
Optical Rotation:-3° to -9° (c=1, MeOH)
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 5mg/mL; H2O: <1mg/mL; EtOH: 58mg/mL
Application(s):Selective 5-hydroxytryptamine 1B/1D (5-HT1B/1D) receptor agonist
Form:Free Base

REVIEW
 A selective serotonin receptor agonist of the 1B and 1D subtypes.

REFERENCES
[1]Dalpiaz A, Marchetti N, Cavazzini A, Pasti L, Velaga S, Gavini E, Beggiato S, Ferraro L (2012). Quantitative determination of zolmitriptan in rat blood and cerebrospinal fluid by reversed phase HPLC-ESI-MS/MS analysis: application to in vivo preclinical pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 901:72-8. PMID 22743338.
[2] Lionetto L, Casolla B, Mastropietri F, D'Alonzo L, Negro A, Simmaco M, Martelletti P (2012). Pharmacokinetic evaluation of zolmitriptan for the treatment of migraines. Expert Opin Drug Metab Toxicol. 8(8):1043-50. PMID 22762358.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of March 29, 2023

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS Request COA

⚠️
These chemical products are for research and development use only. They are not for diagnostic, therapeutic, cosmetic, or human and animal uses. They are not sold to individuals. Additional restrictions may apply.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information.


CATEGORIES
 APIs and Bioactives > Serotonin Agonists


PubChem