128-13-2 Ursodeoxycholic acid AKSci J10139
 
 
Loading Please Wait...
  J10139    AKSci Reference Standard
Ursodeoxycholic acid
, 99%, powder
 
Ursodiol
UDCA
Ursosan
more..




IDENTITY
CAS Number:128-13-2
MDL Number:MFCD00003680
MF:C24H40O4
MW:392.57
EINECS:204-879-3
BRN:3219888
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99%, powder
Physical Form (at 20°C):Solid
Melting Point:203-206°C
Optical Rotation:+57-+62° (c=2,EtOH)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 79mg/mL; H2O: <1mg/mL; EtOH: 79mg/mL
Application(s):Apoptosis inhibitor
Form:Free Base

REVIEW

 One of the secondary bile acids, which are metabolic byproducts of intestinal bacteria. The drug reduces cholesterol absorption and is used to dissolve (cholesterol) gallstones in patients who want an alternative to surgery.

REFERENCES
[1]Chappell LC, Gurung V, Seed PT, Chambers J, Williamson C, Thornton JG; PITCH Study Consortium (2012). Ursodeoxycholic acid versus placebo, and early term delivery versus expectant management, in women with intrahepatic cholestasis of pregnancy: semifactorial randomised clinical trial. BMJ. 344:e3799. PMID 22695903.
[2] Peir?-Jord?n R, Krishna-Subramanian S, Hanski ML, L?scher-Firzlaff J, Zeitz M, Hanski C (2012). The chemopreventive agent ursodeoxycholic acid inhibits proliferation of colon carcinoma cells by suppressing c-Myc expression. Eur J Cancer Prev. 21(5):413-22. PMID 22395148.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of April 15, 2024

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.



CATEGORIES

 APIs and Bioactives > Bile Acids


PubChem