[77-53-2] (+)-Cedrol AKSci J10131
 
 
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  J10131    
(+)-Cedrol
, 99% (GC)
 



IDENTITY
CAS Number:[77-53-2]
MDL Number:MFCD00062952
MF:C15H26O
MW:222.37
EINECS:201-035-6
BRN:2206347
SPECIFICATIONS & PROPERTIES
Purity:99% (GC)
Available Spectra:FT-IR, GCMS, GC, Polarimetry
Physical Form:White crystales
Melting Point:86-87°C
Optical Rotation:+10.5°±1°, (c=5, in chloroform)
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Application(s):A major component of cedarwood oil

REVIEW

 (+)-Cedrol is a sesquiterpene natural product isolated from cedarwood oil extracts of Juniper species trees. As a terpene natural product (+)-Cedrol is a fragrant compound with effects upon animals, and Cedrol (unspecified enantiomer) has been demonstrated to produce autonomic effects, decreasing heart rate, systolic blood pressure, diastolic blood pressure, and respiratory rate in humans. The human skin microbial flora Staphylococcus epidermidis is demonstrated to stereospecifically hydroxylate (+)-Cedrol at the C-3 position. In a study concerning antiproliferative effects of essential oils, (+)-Cedrol was identified as one of the terpene compounds showing activity against human renal adenocarcinoma and amelanotic melanoma cell proliferation.

REFERENCES
[1]Stork, G. and Clark, F.H. Jr. 1961. J. Am. Chem. Soc. 83: 3114-3125.
[2] Dayawansa, S., et al. 2003. Auton Neurosci. 108: 79-86. PMID: 14614968.
[3] Miyazawa, M., et al. 2003. Nat. Prod. Res. 17: 313-317. PMID: 14526908.
[4] Eller, F.J. and Taylor, S.L. 2004. J. Agric. Food Chem. 52: 2335-2338. PMID: 15080642.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of August 22, 2017


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CATEGORIES

 Specialty Chemicals > Flavors and Fragrances
 APIs and Bioactives > Terpenes


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