REVIEW Prednisolone is a corticosteroid drug with predominant glucocorticoid and low mineralocorticoid activity, making it useful for the treatment of a wide range of inflammatory and auto-immune conditions. Prednisolone irreversibly binds with glucocorticoid receptors (GR) alpha and beta for which they have a high affinity.
Klaasen R, Herenius MM, Wijbrandts CA, de Jager W, van Tuyl LH, Nurmohamed MT, Prakken BJ, Gerlag DM, Tak PP (2012). Treatment-specific changes in circulating adipocytokines: a comparison between tumour necrosis factor blockade and glucocorticoid treatment for rheumatoid arthritis. Ann Rheum Dis. 71(9):1510-6. PMID 22440821.
Ahmed HH, Morcos NY, Eskander EF, Seoudi DM, Shalby AB (2012). Potential role of leptin against glucocorticoid-induced secondary osteoporosis in adult female rats. Eur Rev Med Pharmacol Sci. 16(10):1446-52. PMID 23104664.
For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.