50-53-3 Chlorpromazine AKSci J10069
 
 
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  J10069    AKSci Reference Standard
Chlorpromazine, 99% (HPLC), powder
 
Largactil
Contomin
Thorazine
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IDENTITY
CAS Number:50-53-3
MDL Number:MFCD00133295
MF:C17H19ClN2S
MW:318.86
EINECS:200-045-8
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC), powder
Physical Form (at 20°C):Solid
Melting Point:55-62°C
Boiling Point:195-205°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
UN #:UN2811
Hazard Class:6.1; Poison
Packing Group:III
A hazmat fee may apply depending on the amount ordered, as indicated in the list of package sizes.

BIOLOGICAL INFO
Solubility:EtOH: 140mg/mL
Application(s):Antiemetic; Antipsychotic Agent; D2 dopamine receptor antagonist; H1 histamine receptor antagonist
Form:Free Base

REVIEW
 Chlorpromazine is a dopamine antagonist of the typical antipsychotic class of medications possessing additional antiadrenergic, antiserotonergic, anticholinergic and antihistaminergic properties used to treat schizophrenia.

REFERENCES
[1]Trautwein C, Kümmerer K (2012). Degradation of the tricyclic antipsychotic drug chlorpromazine under environmental conditions, identification of its main aquatic biotic and abiotic transformation products by LC-MSn and their effects on environmental bacteria. J Chromatogr B Analyt Technol Biomed Life Sci. 889-890:24-38. PMID 22342447.
[2] Hauck MJ, Lee HH, Timoney PJ, Shoshani Y, Nunery WR (2012). Neurotrophic corneal ulcer after retrobulbar injection of chlorpromazine. Ophthal Plast Reconstr Surg. 8(3):e74-6. PMID 22082589.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of December 8, 2023

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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⚠️
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CATEGORIES
 APIs and Bioactives > Dopamine Antagonists, Antipsychotics


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