REVIEW Levofloxacin is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase iv, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division.
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Miyake T, Ito N, Tajima K, Goto H, Furukawa T (2012). Comparison of moxifloxacin and levofloxacin in an epithelial disorder model using cultured rabbit corneal epithelial cell sheets. Graefes Arch Clin Exp Ophthalmol. 250(7):1035-41. PMID 22282216.
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Sun J, Song M, Feng J, Pi Y (2012). Highly efficient degradation of ofloxacin by UV/Oxone/Co2+ oxidation process. Environ Sci Pollut Res Int. 19(5):1536-43. PMID 22072118.
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Milder E, Vander J, Shah C, Garg S (2012). Changes in antibiotic resistance patterns of conjunctival flora due to repeated use of topical antibiotics after intravitreal injection. Ophthalmology. 119(7):1420-4. PMID 22420958.
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