164656-23-9 Dutasteride AKSci J10036
 
 
Loading Please Wait...
  J10036    AKSci Reference Standard
Dutasteride
, >98% (HPLC), powder
 
Avodart®




IDENTITY
CAS Number:164656-23-9
MDL Number:MFCD00937869
MF:C27H30F6N2O2
MW:528.53
EINECS:238-483-7
SPECIFICATIONS & PROPERTIES
Purity:>98% (HPLC), powder
Spectra:LCMS, HPLC
Physical Form:White to off-white crystalline powder
Melting Point:240-252°C
Long-Term Storage:Store long-term at -20°C

BIOLOGICAL INFO
Solubility:DMSO: 62mg/mL; H2O: <1mg/mL; EtOH: 6mg/mL
Application(s):5-alpha Reductase inhibitor
Form:Free Base

REVIEW

 A dual 5-alpha-reductase inhibitor that blocks both type 1 and type 2 5-alpha-reductase isoenzymes. These enzymes are responsible for converting testosterone into dihydrotestosterone (DHT) in the prostate.

REFERENCES
[1]Kaplan SA, Lee RK, Chung DE, Te AE, Scherr DS, Tewari A, Vaughan ED (2012). Prostate biopsy in response to a change in nadir prostate specific antigen of 0.4 ng/ml after treatment with 5a-reductase inhibitors markedly enhances the detection rate of prostate cancer. J Urol. 188(3):757-61. PMID 22818135.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of July 11, 2020

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS

For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.


CATEGORIES

 APIs and Bioactives > Antiandrogens


PubChem