164656-23-9 Dutasteride AKSci J10036
 
 
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  J10036    AKSci Reference Standard
Dutasteride
, >98% (HPLC), powder
 
Avodart®




IDENTITY
CAS Number:164656-23-9
MDL Number:MFCD00937869
MF:C27H30F6N2O2
MW:528.53
EINECS:238-483-7
SPECIFICATIONS & PROPERTIES
Purity:>98% (HPLC), powder
Spectra:LCMS, HPLC
Physical Form:White to off-white crystalline powder
Melting Point:240-252°C
Long-Term Storage:Store long-term at -20°C

BIOLOGICAL INFO
Solubility:DMSO: 62mg/mL; H2O: <1mg/mL; EtOH: 6mg/mL
Application(s):5-alpha Reductase inhibitor
Form:Free Base

REVIEW

 A dual 5-alpha-reductase inhibitor that blocks both type 1 and type 2 5-alpha-reductase isoenzymes. These enzymes are responsible for converting testosterone into dihydrotestosterone (DHT) in the prostate.

REFERENCES
[1]Kaplan SA, Lee RK, Chung DE, Te AE, Scherr DS, Tewari A, Vaughan ED (2012). Prostate biopsy in response to a change in nadir prostate specific antigen of 0.4 ng/ml after treatment with 5a-reductase inhibitors markedly enhances the detection rate of prostate cancer. J Urol. 188(3):757-61. PMID 22818135.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of March 22, 2019

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Antiandrogens


PubChem