REVIEW A loop diuretic used in the treatment of congestive heart failure and edema. Furosemide acts by inhibiting NKCC2, the luminal Na-K-2Cl symporter in the thick ascending limb of the loop of Henle.
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Sigmund EE, Vivier PH, Sui D, Lamparello NA, Tantillo K, Mikheev A, Rusinek H, Babb JS, Storey P, Lee VS, Chandarana H (2012). Intravoxel incoherent motion and diffusion-tensor imaging in renal tissue under hydration and furosemide flow challenges. Radiology. 263(3):758-69. PMID 22523327.
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