138402-10-5 Triphenyl irbesartan AKSci I998
 
 
Loading Please Wait...
  I998    AKSci Bulk Reagent
Triphenyl irbesartan
, 98%
 



IDENTITY
CAS Number:138402-10-5
MDL Number:MFCD08460099
MF:C44H42N6O
MW:670.84
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Melting Point:142-148°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 Triphenyl irbesartan is an advanced intermediate used in the preparation of irbesartan, an angiotension II antagonist, used in the treatment of hypertension.

REFERENCES
[1]Bernhart, Claude; Breliere, Jean Claude; Clement, Jacques; Nisato, Dino; Perreaut, Pierre; Preparation of N-(carboxybiphenylylmethyl)spiro[cycloalkane-imidazolinone] derivatives and analogs as angiotensin II inhibitors. PCT Int. Appl. (1991), WO 9114679 A1 19911003.
[2] Spinale, Francis Guy; N-substituted spirocyclopentaneimidazolinone derivatives for the treatment or prevention of cardiac arrhythmia. Can. Pat. Appl. (1996), CA 2154807 A1 19960223.
[3] Castro, Bertrand; Dormoy, Jean-Robert; Mach, Mateusz; Makosza, Mieczyslaw; Pankowski, Jacek; Preparation of 2-oxazolinyl-4'-phthalimidomethylbiphenyls. PCT Int. Appl. (1999), WO 9906398 A1 19990211.
[4] Nisnevich, Gennady; Rukhman, Igor; Pertsikov, Boris; Kaftanov, Julia; Dolitzky, Ben-Zion; Shapiro, Eugeny; Yahalomi, Bonit; Synthesis of irbesartan. PCT Int. Appl. (2004), WO 2004007482 A2 20040122.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of March 26, 2023


Download SDS Request COA

⚠️
These chemical products are for research and development use only. They are not for diagnostic, therapeutic, cosmetic, or human and animal uses. They are not sold to individuals. Additional restrictions may apply.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information.



CATEGORIES

 APIs and Bioactives > Angiotensin Receptor Blockers, Hypertension


PubChem
  @PubMed