138402-10-5 Triphenyl irbesartan AKSci I998
 
 
Loading Please Wait...
  I998    
Triphenyl irbesartan, 98%
 



IDENTITY
CAS Number:138402-10-5
MDL Number:MFCD08460099
MF:C44H42N6O
MW:670.84
SPECIFICATIONS & PROPERTIES
Purity:98%
Physical Form:White powder
Melting Point:142-148°C
Long-Term Storage:Store long-term at -20°C

REVIEW
 Triphenyl irbesartan is an advanced intermediate used in the preparation of irbesartan, an angiotension II antagonist, used in the treatment of hypertension.

REFERENCES
[1]Bernhart, Claude; Breliere, Jean Claude; Clement, Jacques; Nisato, Dino; Perreaut, Pierre; Preparation of N-(carboxybiphenylylmethyl)spiro[cycloalkane-imidazolinone] derivatives and analogs as angiotensin II inhibitors. PCT Int. Appl. (1991), WO 9114679 A1 19911003.
[2] Spinale, Francis Guy; N-substituted spirocyclopentaneimidazolinone derivatives for the treatment or prevention of cardiac arrhythmia. Can. Pat. Appl. (1996), CA 2154807 A1 19960223.
[3] Castro, Bertrand; Dormoy, Jean-Robert; Mach, Mateusz; Makosza, Mieczyslaw; Pankowski, Jacek; Preparation of 2-oxazolinyl-4'-phthalimidomethylbiphenyls. PCT Int. Appl. (1999), WO 9906398 A1 19990211.
[4] Nisnevich, Gennady; Rukhman, Igor; Pertsikov, Boris; Kaftanov, Julia; Dolitzky, Ben-Zion; Shapiro, Eugeny; Yahalomi, Bonit; Synthesis of irbesartan. PCT Int. Appl. (2004), WO 2004007482 A2 20040122.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of July 8, 2020


Download SDS

For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.


CATEGORIES
 APIs and Bioactives > Angiotensin Receptor Blockers, Hypertension


PubChem
  @PubMed