96034-64-9 (2S,4S)-2-(Dimethylaminocarbonyl)-4-mercapto-1-(4'-nitrobenzyloxycarbonyl)-1-pyrrolidine AKSci I741
 
 
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  I741    
(2S,4S)-2-(Dimethylaminocarbonyl)-4-mercapto-1-(4'-nitrobenzyloxycarbonyl)-1-pyrrolidine
, 98%
 
4-Nitrobenzyl (2S,4S)-2-(Dimethylcarbamoyl)-4-mercapto-1-pyrrolidinecarboxylate




IDENTITY
CAS Number:96034-64-9
MDL Number:MFCD08063348
MF:C15H19N3O5S
MW:353.39
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form:White powder
Melting Point:119°C (246°F)
Optical Rotation:+8.5 ° - +10.5 ° (c=1% w/v in Chloroform)
Long-Term Storage:Store at room temperature
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

REVIEW

 (2S,4S)-2-(Dimethylaminocarbonyl)-4-mercapto-1-(4'-nitrobenzyloxycarbonyl)-1-pyrrolidine is an advanced intermediate for the side chain used in the preparation of the carbopenem Meropenem.

REFERENCES
[1]Tewari, Neera; George, Vinod; Mane, Avinash Sheshrao; Meeran, Hashim Nizar Poovanathil Nagoor; Prasad, Mohan A process for the preparation of carbapenem compounds PCT Int. Appl. (2007), WO 2007029084 A2 20070315.
[2] Ageno, Takafumi; Okajima, Motonori; Koga, Teruyoshi Improved process for producing intermediate for side chain of carbapenem PCT Int. Appl. (2010), WO 2010073706 A1 20100701.
[3] Sureshkumar, Kanagaraj; Senthilkumar, Udayampalayam Palanisamy; Maruthi Chandrasekhara Kishor, Addanki; Vinod Babu, Dasari; John Bosco, John Peter; Karthikeyan, Lakshmi Narayanan An improved process for the preparation of carbapenem antibiotic PCT Int. Appl. (2010), WO 2010097686 A1 20100902.
[4] Karale, Sanjay Nivrutti; Jangale, Arvind Atamaram; Kaldate, Ram Dattatraya An improved process for the preparation of meropenem PCT Int. Appl. (2011), WO 2011141847 A1 20111117.

GHS

Pictograms

Signal Word
None

Hazard Statements
None

Precautionary Statements
Not available


Current as of April 22, 2021


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CATEGORIES

 APIs and Bioactives > Carbapenems


PubChem
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