11015-37-5 Flavomycin, 8% over CaCO3, Potency 72000u/g AKSci I020
 
 
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  I020    AKSci Bulk Reagent
Flavomycin, 8% over CaCO3, Potency 72000u/g
 
Bambermycins
Moenomycin




IDENTITY
CAS Number:11015-37-5
MDL Number:MFCD01742468
MF:C69H107N4O35P
MW:1583.57
EINECS:234-246-7
SPECIFICATIONS & PROPERTIES
Physical Form (at 20°C):Solid
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):An antibiotic and selective inhibitor of the transglycosylation step

REVIEW

 Flavomycin (Bambermycin) is a complex of antibiotics obtained from Streptomyces bambergiensis. The complex consists mainly of moenomycins A and C. Flavomycin is effective against Gram-positive bacteria, but it does not have significant action against Lactobacillus, Bifidobacterium, and other protective bacteria. Its mechanism of action involves inhibition of bacterial wall synthesis, in particular, the Transglycosylation step in Peptidoglycan Biosynthesis. Flavomycin is used as a feed supplement for broilers, laying hens, turkey hens, ducks, pheasants, pigs, calves, and fattening steers.

REFERENCES
[1]Pilloud M Antibiotics and chemotherapeutic agents-from research to practice. VII. Some remarks to practitioners on the properties of polymyxins, lincosanides, spectinomycin, synergistines, bacitracin, novobiocin and flavomycin Schweizer Archiv fur Tierheilkunde (1983), 125(6), 371-82.
[2] Jahn, Wilhelm Antibiotic Flavomycin: a new type of feed additive Tieraerztliche Umschau (1970), 25(10), 503-6.
[3] Schlegel, R.; Fuegner, Rosemarie; Bradler, Gertraud; Thrum, H. Flavomycin, a new polyene antibiotic from Streptomyces roseoflavus Zeitschrift fuer Allgemeine Mikrobiologie (1971), 11(8), 661-70.
[4] Goldman RC, Gange D. Inhibition of transglycosylation involved in bacterial peptidoglycan synthesis. Curr Med Chem. 2000 Aug;7(8):801-20.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
None

Hazard Statements
H413

Precautionary Statements
P273; P501


Current as of July 13, 2024


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CATEGORIES

 APIs and Bioactives > Antibacterials


PubChem
  @PubMed