Selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II
Form:
Free Base
REVIEW An an immunosuppressant and prodrug of mycophenolic acid, used extensively in transplant medicine. Mycophenolate mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II
REFERENCES
[1]
Clayton PA, McDonald SP, Chapman JR, Chadban SJ (2012). Mycophenolate versus azathioprine for kidney transplantation: a 15-year follow-up of a randomized trial. Transplantation. 94(2):152-8. PMID 22728292.
[2]
Sodikoff JB, Keilin SA, Cai Q, Bharmal SJ, Lewis MM, Raju GS, Willingham FF (2012). Mycophenolate mofetil for maintenance of remission in steroid-dependent autoimmune pancreatitis. World J Gastroenterol. 18(18):2287-90. PMID 22611324.
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