128794-94-5 Mycophenolate mofetil AKSci H944

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H944 AKSci Reference Standard
Mycophenolate mofetil, >98% (HPLC)

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RS 61443

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IDENTITY
CAS Number:	128794-94-5
MDL Number:	MFCD00867568
MF:	C23H31NO7
MW:	433.49

SPECIFICATIONS & PROPERTIES
Purity:	>98% (HPLC)
Spectra:	FT-IR, LCMS, HPLC
Physical Form:	White to off-white powder
Melting Point:	93-97°C
Long-Term Storage:	Store at room temperature

BIOLOGICAL INFO
Application(s):	Selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II
Form:	Free Base

REVIEW
An an immunosuppressant and prodrug of mycophenolic acid, used extensively in transplant medicine. Mycophenolate mofetil is a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase I/II

REFERENCES

[1]	Clayton PA, McDonald SP, Chapman JR, Chadban SJ (2012). Mycophenolate versus azathioprine for kidney transplantation: a 15-year follow-up of a randomized trial. Transplantation. 94(2):152-8. PMID 22728292.
[2]	Sodikoff JB, Keilin SA, Cai Q, Bharmal SJ, Lewis MM, Raju GS, Willingham FF (2012). Mycophenolate mofetil for maintenance of remission in steroid-dependent autoimmune pancreatitis. World J Gastroenterol. 18(18):2287-90. PMID 22611324.

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