70356-03-5 Cefaclor monohydrate AKSci H800
 
 
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  H800    
Cefaclor monohydrate
, 98% (HPLC)
 



IDENTITY
CAS Number:70356-03-5
MDL Number:MFCD00071999
MF:C15H14ClN3O4S.H20
MW:385.82
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Spectra:LCMS, HPLC
Physical Form:White to off-white to light yellow powder
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:H2O
Application(s):Antibiotic, a potentially useful antimicrobial agent for in vitro studies of pathogens
Form:Hydrate

REVIEW

 Cefaclor, like the penicillins, is a beta-lactam antibiotic. By binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, it inhibits the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall autolytic enzymes such as autolysins. It is possible that cefaclor interferes with an autolysin inhibitor.

REFERENCES
[1]Hebert AA, Sigman ES, Levy ML: Serum sickness-like reactions from cefaclor in children. J Am Acad Dermatol. 1991 Nov;25(5 Pt 1):805-8.
[2] Parra FM, Igea JM, Martin JA, Alonso MD, Lezaun A, Sainz T: Serum sickness-like syndrome associated with cefaclor therapy. Allergy. 1992 Aug;47(4 Pt 2):439-40.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of October 18, 2021


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CATEGORIES

 APIs and Bioactives > Antibacterials, Cephalosporins


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