19767-45-4 2-Mercaptoethanesulfonic acid sodium salt AKSci H751
 
 
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  H751    AKSci Bulk Reagent
2-Mercaptoethanesulfonic acid sodium salt, 98% (HPLC)
 
Sodium 2-mercaptoethanesulfonate
Coenzyme M sodium salt
Uromitexan
more..
IDENTITY
CAS Number:19767-45-4
MDL Number:MFCD00007535
MF:C2H5NaO3S2
MW:164.18
EINECS:243-285-9
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:259-275°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 33mg/mL; H2O: 7mg/mL; EtOH: <1mg/mL
Application(s):Hemorrhagic cystitis inhibitor
Form:Free Base

REVIEW
 An organosulfur compound used in cancer chemotherapy involving cyclophosphamide and ifosfamide as an adjuvant. Mesna is used therapeutically to reduce the incidence of haemorrhagic cystitis and haematuria when a patient receives ifosfamide or cyclophosphamide for cancer chemotherapy.

REFERENCES
[1]Vepachedu VR, Ferry JG (2012). Role of the fused corrinoid/methyl transfer protein CmtA during CO-dependent growth of Methanosarcina acetivorans. J Bacteriol. 194(16):4161-8. PMID 22636775.
[2] Cutler MJ, Urquhart BL, Velenosi TJ, Meyer Zu Schwabedissen HE, Dresser GK, Leake BF, Tirona RG, Kim RB, Freeman DJ (2012). In vitro and in vivo assessment of renal drug transporters in the disposition of mesna and dimesna. J Clin Pharmacol. 52(4):530-42. PMID 21505084.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of November 21, 2024


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CATEGORIES
 APIs and Bioactives > Chemotherapeutics, Mucokinetics


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