130018-87-0 Levocetirizine dihydrochloride AKSci H739
 
 
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  H739    
Levocetirizine dihydrochloride
, 98%
 
(-)-Cetirizine dihydrochloride
2-[2-[4-[(R)-(4-chlorophenyl)-phenyl-methyl]piperazin-1-yl]ethoxy]acetic acid dihydrochloride




IDENTITY
CAS Number:130018-87-0
MDL Number:MFCD07366507
MF:C21H25ClN2O3.2HCl
MW:461.81
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Spectra:LCMS, HPLC
Physical Form:White to almost white crystalline powder
Melting Point:229°C
Optical Rotation:-12.79° (c=1, H2O)
Long-Term Storage:Store long-term in a cool, dry place
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:H2O: =23 mg/mL
Form:2HCl salt

REVIEW

 A nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic.

REFERENCES
[1]Arayne, M. Saeed; Medicinal Chemistry Research 2010, V19(9), P1064-1073

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H302; H400; H410

Precautionary Statements
P264; P270; P273; P301+P312; P330; P391; P501


RELATED PRODUCTS
A547Cetirizine dihydrochloride

Current as of March 2, 2021


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CATEGORIES

 APIs and Bioactives > Antihistamines


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