29608-49-9 Almitrine dimesilate AKSci H525
 
 
Loading Please Wait...
  H525    
Almitrine dimesilate, 98%
 
Almitrine bismesylate
Almitrine dimesylate
Almitrine dimethanesulfonate
IDENTITY
CAS Number:29608-49-9
MDL Number:MFCD01679060
MF:C26H29F2N7.2CH4O3S
MW:669.76
EINECS:249-726-1
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98%
Physical Form (at 20°C):Solid
Melting Point:229-231°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Application(s):Respiratory System Agent; Peripheral Chemoreceptors Agonist
Form:Dimesylate

REVIEW
 Almitrine dimesilate is a respiratory stimulant that enhances respiration by acting as an agonist of peripheral chemoreceptors located on the carotid bodies. The drug increases arterial oxygen tension while decreasing arterial carbon dioxide tension in patients with chronic obstructive pulmonary disease. It may also prove useful in the treatment of nocturnal oxygen desaturation without impairing the quality of sleep.

REFERENCES
[1]Labrid, C. Almitrine dimesylate mechanism of action. Clinical Respiratory Physiology. (1982) 18(Suppl. 4): 299-306.
[2] Bromet, N.; Singlas, E. Clinical pharmacokinetics of almitrine bismesylate. Presse Medicale. (1984) 13(34): 2071-7.
[3] Marmo, E. The experimental and clinical pharmacological properties of almitrine bismesylate. Riforma Medica. (1986) 101(12): 509-39.
[4] s-Triazine derivatives, and their analeptic respiratory activity Belg. (1970), BE 739283 A 19700323.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of April 18, 2024


Download SDS Request COA

All products are stocked and shipped from San Francisco Bay Area, California, USA.

⚠️
All products are for research and development use only, not for any other uses, and must be handled by technically-qualified persons.

These products are explicitly not intended to be used in foods and/or cosmetics and/or drugs (human and veterinary) and/or consumer products and/or biocides and/or pesticides of any kind unless explicitly stated otherwise.

Products are not sold to individuals. We do not ship to residential addresses. Consumer orders will be cancelled without notice.

New customers undergo an internal onboarding process. As part of this process, new customers may be asked for more information. Additional restrictions may apply.


CATEGORIES
 APIs and Bioactives >


PubChem