53-16-7 Estrone AKSci H064
 
 
Loading Please Wait...
  H064    
Estrone
, 98% (HPLC)
 
3-Hydroxy-1,3,5(10)-estratrien-17-one
1,3,5(10)-Estratrien-3-ol-17-one
Folliculin Oestrone




IDENTITY
CAS Number:53-16-7
MDL Number:MFCD00003620
MF:C18H22O2
MW:270.37
EINECS:200-164-5
BRN:1915077
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Physical Form:White to off-white crystalline powder
Melting Point:258-263°C
Optical Rotation:+158° to +165° (c=1, Dioxane)
Long-Term Storage:Store long-term at room temperature
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 54mg/mL; H2O: <1mg/mL; EtOH: <1mg/mL
Application(s):Estrogen receptor
Form:Free Base

REVIEW

 An estrogenic hormone secreted by the ovary as well as adipose tissue.

REFERENCES
[1]Axon A, May FE, Gaughan LE, Williams FM, Blain PG, Wright MC (2012). Tartrazine and sunset yellow are xenoestrogens in a new screening assay to identify modulators of human oestrogen receptor transcriptional activity. Toxicology. 298(1-3):40-51. PMID 22562034.
[2] Engler-Chiurazzi EB, Talboom JS, Braden BB, Tsang CW, Mennenga S, Andrews M, Demers LM, Bimonte-Nelson HA (2012). Continuous estrone treatment impairs spatial memory and does not impact number of basal forebrain cholinergic neurons in the surgically menopausal middle-aged rat. Horm Behav. 62(1):1-9. PMID 22522079.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H350; H360

Precautionary Statements
P201; P202; P281; P308+P313; P405; P501


Current as of August 15, 2020


Download SDS

For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.

WARNING: Attention California residents: This product can expose you to chemicals including Estrone, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.


CATEGORIES

 APIs and Bioactives > Steroid Hormones


PubChem