59338-87-3 Alizapride hydrochloride AKSci H002
 
 
Loading Please Wait...
  H002    AKSci Reference Standard
Alizapride hydrochloride
, 99% (HPLC)
 



IDENTITY
CAS Number:59338-87-3
MDL Number:MFCD02183928
MF:C16H21N5O2.HCl
MW:351.83
EINECS:261-710-6
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Spectra:FT-IR, LCMS, HPLC
Physical Form:White powder
Melting Point:207-210°C
Long-Term Storage:Store long-term at room temperature
HAZARDOUS MATERIALS INFORMATION
Not hazardous material

BIOLOGICAL INFO
Form:HCl salt

REVIEW

 The anti-emetic action of Alizapride is due to its antagonist activity at D2 receptors in the chemoreceptor trigger zone (CTZ) in the central nervous system (CNS)-this action prevents nausea and vomiting triggered by most stimuli. Structurally similar to metoclopramide and, therefore, shares similar other atributres related to emesis and prokinetics.

REFERENCES
[1]Bleiberg H, Gerard B, Dalesio O, Crespeigne N, Rozencweig M: Activity of a new antiemetic agent: alizapride. A randomized double-blind crossover controlled trial. Cancer Chemother Pharmacol. 1988;22(4):316-20.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of October 28, 2020

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


Download SDS

For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.


CATEGORIES

 APIs and Bioactives > Dopamine Antagonists


PubChem