107753-78-6 Zafirlukast AKSci G674
 
 
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  G674    AKSci Reference Standard
Zafirlukast
, 98% (HPLC)
 
N-[3-[[2-Methoxy-4-[[[(2-methylphenyl)sulfonyl]amino]carbonyl]phenyl]methyl]-1-methyl-1H-indol-5-yl]carbamic acid cyclopentyl ester




IDENTITY
CAS Number:107753-78-6
MDL Number:MFCD00864775
MF:C31H33N3O6S
MW:575.68
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Spectra:FT-IR, LCMS, HPLC
Physical Form:Off-white to light pink powder
Melting Point:138-140°C
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Solubility:DMSO: >=28 mg/mL
Application(s):Leukotriene receptor antagonist (LTRA)

REVIEW

 Zafirlukast is a selective and competitive receptor antagonist of leukotriene D4 and E4 (LTD4 and LTE4), components of slow-reacting substance of anaphylaxis (SRSA). Cysteinyl leukotriene production and receptor occupation have been correlated with the pathophysiology of asthma, including airway edema, smooth muscle constriction, and altered cellular activity associated with the inflammatory process, which contribute to the signs and symptoms of asthma.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H413

Precautionary Statements
P273; P501


Current as of August 19, 2019

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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For research use only. Not for diagnostic or therapeutic use.
Not for human use.


CATEGORIES

 APIs and Bioactives > Leukotrine Receptor Antagonists


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