REVIEW Balofloxacin, an orally active fluoroquinolone antibiotic, has been developed by Choongwae Pharma in Korea for the treatment of urinary tract infection. It functions by inhibiting DNA gyrase, a type II topoisomerase, and topoisomerase IV, which is an enzyme necessary to separate replicated DNA, thereby inhibiting cell division.
REFERENCES
[1]
Nagano, Hiroyuki; Yokota, Takeshi; Katoh, Preparation and testing of 1-cyclopropyl-7-[(3-aminoalkyl)-3-piperidinyl]-4-quinolone-3-carboxylic acids as antibacterials Eur. Pat. Appl. (1989), EP 342675 A2 19891123.
[2]
Ochi, Kiyoshige; Shimizu, Hirohito Preparation of 6-fluoro-7-(heterocyclic amino)-3-quinolonecarboxylic acid derivatives as intermediates for antibacterial agents PCT Int. Appl. (1993), WO 9302055 A1 19930204.
[3]
Nakashima, Mitsuyoshi; Kosuge, Kazuhiro; Umemura, Kazuo; Takiguchi, Yoshiharu; Kondo, Kazunao; Mizuno, Atsuhiro; Uematsu, Toshihiko; Watanabe, Yuuji Clinical pharmacology of antimicrobial pylidonecarboxylic acids. III. Comparative study of newly developed compounds on pharmacokinetics in healthy humans Nippon Kagaku Ryoho Gakkai Zasshi (1995), 43(6), 647-54.
[4]
Iwasaki, Hiroaki; Miyazaki, Shuichi; Tsuji, Akiyoshi; Kaneko, Yasuko; Yamaguchi, Keizo; Goto, Sachiko In vitro and in vivo antibacterial activities of balofloxacin, a novel fluoroquinolone Nippon Kagaku Ryoho Gakkai Zasshi (1995), 43(Suppl. 5), 17-26.
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