91374-20-8 Ropinirole HCl AKSci G394
 
 
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  G394    AKSci Reference Standard
Ropinirole HCl, 99% (HPLC), powder
 
4-[2-(Dipropylamino)ethyl]-1,3-dihydro-2H-indol-2-one hydrochloride, SKF 101468 hydrochloride
IDENTITY
CAS Number:91374-20-8
MDL Number:MFCD01754173
MF:C16H25ClN2O
MW:296.84
SPECIFICATIONS & PROPERTIES
Purity:99% (HPLC), powder
Spectra:NMR, LCMS, FT-IR, HPLC
Physical Form:Light yellow powder
Melting Point:235-243°C
Long-Term Storage:Store at room temperature

BIOLOGICAL INFO
Solubility:H2O: >10 mg/mL
Application(s):Selective dopamine D2 receptors inhibitor
Form:HCl salt

REVIEW
 Ropinirole binds the dopamine receptors D3 and D2. Although the precise mechanism of action of ropinirole as a treatment for Parkinson's disease is unknown, it is believed to be related to its ability to stimulate these receptors in the striatum. This conclusion is supported by electrophysiologic studies in animals that have demonstrated that ropinirole influences striatal neuronal firing rates via activation of dopamine receptors in the striatum and the substantia nigra, the site of neurons that send projections to the striatum.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H302; H410

Precautionary Statements
P264; P270; P273; P301+P312; P330; P391; P501

Current as of July 7, 2020

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES
 APIs and Bioactives > Dopamine Agonists


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