66108-95-0 Iohexol AKSci F971
 
 
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  F971    AKSci UltraPure
Iohexol
, 98% (HPLC)
 
Histodenz
5-(N-2,3-Dihydroxypropylacetamido)-2,4,6-triiodo-N,N''-bis(2,3-dihydroxypropyl)isophthalamide




IDENTITY
CAS Number:66108-95-0
MDL Number:MFCD00077732
MF:C19H26I3N3O9
MW:821.14
EINECS:266-164-2
BRN:2406632
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Physical Form:White to off-white crystalline powder
Melting Point:242-246°C
Long-Term Storage:Store long-term at -20°C

BIOLOGICAL INFO
Application(s):A nonionic contrast agent

REVIEW

 Organic iodine compounds block x-rays as they pass through the body, thereby allowing body structures containing iodine to be delineated in contrast to those structures that do not contain iodine. The degree of opacity produced by these compounds is directly proportional to the total amount (concentration and volume) of the iodinated contrast agent in the path of the x-rays. After intrathecal administration into the subarachnoid space, diffusion of iohexol in the CSF allows the visualization of the subarachnoid spaces of the head and spinal canal. After intravascular administration, iohexol makes opaque those vessels in its path of flow, allowing visualization of the internal structures until significant hemodilution occurs.

REFERENCES
[1]Kawada TK: Iohexol and iopamidol: second-generation nonionic radiographic contrast media. Drug Intell Clin Pharm. 1985 Jul-Aug;19(7-8):525-9.
[2] Shaw DD, Potts DG: Toxicology of iohexol. Invest Radiol. 1985 Jan-Feb;20(1 Suppl):S10-3.
[3] Kormos, Jennifer Lynne; Analytical Chemistry (Washington, DC, United States) 2009, V81(22), P9216-9224

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of February 17, 2020


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For research use only. Not for diagnostic or therapeutic use.
Not for human use.


CATEGORIES

 APIs and Bioactives > Medical Imaging


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