144690-92-6 Trityl olmesartan medoxomil AKSci F351
 
 
Loading Please Wait...
  F351    
Trityl olmesartan medoxomil
, 98% (HPLC)
 
Trityl olmesartan
1H-Imidazole-5-carboxylic acid
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester
more..




IDENTITY
CAS Number:144690-92-6
MDL Number:MFCD09954745
MF:C48H44N6O6
MW:800.9
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Spectra:LCMS, HPLC
Physical Form:White or almost white powder
Melting Point:108-114°C
Long-Term Storage:Store long-term at 2-8°C

REVIEW

 Trityl olmesartan medoxomil is a key intermediate used in the preparation of olmesartan medoxomil, an angiotension II receptor antagonist, used in the treatment of hypertension.

REFERENCES
[1]Yanagisawa, Hiroaki; Shimoji, Yasuo; Fujimoto, Koichi; Kanazaki, Takuro; Anemiya, Yoshiya; Koike, Hiroyuki; Sada, Toshio, Prepeparation of 1-[(carboxy-biphenylyl)methyl]imidazole-5-carboxylates and analogs as angiotensin II antagonists. Eur. Pat. Appl. (1992), EP 503785 A1 19920916.
[2] Zhang, Fuli; Wu, Taizhi Preparation of olmesartan medoxomil. PCT Int. Appl. (2004), WO 2004085428 A1 20041007.
[3] Hedvati, Lilach; Pilarsky, Gideon; Process for the preparation of olmesartan medoxomil. PCT Int. Appl. (2006), WO 2006029056 A1 20060316.
[4] Ramanjaneyulu, Gorantla Seeta; Mohan, Bandari; Ray, Purna Chandra; Sethi, Madhuresh Kumar; Rawat, Vijendra Singh; Krishna, Yerramalla Raja; Lakshminarayana, Vemula; Srinivas, Mamidi; Process for the preparation of olmesartan medoxomil. PCT Int. Appl. (2007), WO 2007148344 A2 20071227.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of July 4, 2020


Download SDS

For research use only. Not for diagnostic or therapeutic use. Not for human use. AK Scientific, Inc. does not sell to individuals. If you are a first-time customer, please email for review at least two official business documents issued by your local jurisdiction, state/province, or country.


CATEGORIES

 APIs and Bioactives > Angiotensin Receptor Blockers


PubChem