37339-90-5 Lentinan, tech. AKSci E878
 
 
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  E878    
Lentinan, tech.
 



IDENTITY
CAS Number:37339-90-5
MDL Number:MFCD01773536
MF:(C42H72O36)n
SPECIFICATIONS & PROPERTIES
Physical Form (at 20°C):Brown powder
Melting Point:165°C
Density:1.8
Refractive Index:1.67
Long-Term Storage:Store at room temperature
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:Soluble in aqueous alkali, formic acid.

REVIEW

 Lentinan is an anti-tumor polysaccharide isolated from the fruit body of the shiitake mushroom Lentinula edodes. It manifests marked antitumor and antimetastatic activity in numerous tumor/host systems, and prevents chemical and viral carcinogenesis. Modulation of immune or vascular functions is involved in its antitumor effects. Limited clinical studies of cancer patients have associated lentinan with a higher survival rate, higher quality of life, and lower re-occurrence of cancer.

REFERENCES
[1]Chihara G; Hamuro J; Maeda Y Y; Shiio T; Suga T; Takasuka N; Sasaki T Antitumor and metastasis-inhibitory activities of lentinan as an immunomodulator: an overview Cancer detection and prevention. Supplement : official publication of the International Society for Preventive Oncology, Inc (1987), 1, 423-43.
[2] Lien EJ.Fungal metabolites and Chinese herbal medicine as immunostimulants. Prog Drug Res. 1990;34:395-420.
[3] Kaneko Y, Chihara G.Potentiation of host resistance against microbial infections by lentinan and its related polysaccharides. Adv Exp Med Biol. 1992;319:201-15.
[4] Chihara G Recent progress in immunopharmacology and therapeutic effects of polysaccharides. Developments in biological standardization (1992), 77, 191-7.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of December 4, 2021


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CATEGORIES

 APIs and Bioactives > Chemotherapeutics
 Carbohydrates > Polysaccharides
 Carbohydrates > Polysaccharides


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