36923-17-8 7-Amino-3-nor-3-cephem-4-carboxylic acid AKSci E864
 
 
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  E864    
7-Amino-3-nor-3-cephem-4-carboxylic acid
, 98% (HPLC)
 
(6R-trans)-7-Amino-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-ANCA




IDENTITY
CAS Number:36923-17-8
MDL Number:MFCD08063340
MF:C7H8N2O3S
MW:200.22
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:227-232°C
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW

 An advanced beta lactam cephalosporin intermediate used in the preparation of beta lactam antibiotics.

REFERENCES
[1]Takaya, Takao; Kawauchi, Hiromu; Masugi, Takashi Cephalosporin compounds Jpn. Kokai Tokkyo Koho (1979), JP 54003087 A 19790111.
[2] Duerckheimer, Walter; Bormann, Dieter; Ehlers, Eberhard; Schrinner, Elmar; Heymes, Rene Cephem derivatives and processes for their manufacture Brit. UK Pat. Appl. (1980), GB 2028305 A 19800305.
[3] Hannah, John; Johnson, Charles R.; Wagner, Arthur F.; Walton, Edward Quaternary heterocyclylamino beta-lactams: a generic alternative to the classical acylamino side chain Journal of Medicinal Chemistry (1982), 25(4), 457-69.
[4] Takasugi, Hisashi; Kochi, Hiromu; Masugi, Takashi; Nakano, Hiroshi; Takaya, Takao Studies on beta-lactam antibiotics. VII. Effect on antibacterial activity of the oxime O-substituents with various functional groups in the 7beta-[(Z)-2-(2-amino-4-thiazolyl)-2-oxyiminoacetamido]cephalosporins Journal of Antibiotics (1983), 36(7), 846-54.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of October 15, 2024


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CATEGORIES

 APIs and Bioactives > Cephalosporins


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