REVIEW Rasagiline mesylate is an chiral, single enantiomer irreversible inhibitor of monoamine oxidase. Rasagiline is an irreversible inhibitor of monoamine oxidase used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases. It is selective for MAO type B over type A by a factor of fourteen.
REFERENCES
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Zagmutt FJ, Tarrants ML (2012). Indirect comparisons of adverse events and dropout rates in early Parkinson's disease trials of pramipexole, ropinirole, and rasagiline. Int J Neurosci. 122(7):345-53. PMID 22304415.
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Chen JJ, Wilkinson JR (2012). The monoamine oxidase type B inhibitor rasagiline in the treatment of Parkinson disease: is tyramine a challenge? J Clin Pharmacol. 52(5):620-8. PMID 21628600.
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