1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneacetic acid sodium salt hydrate
SPECIFICATIONS & PROPERTIES
LCMS, FT-IR, HPLC
Off-white to light yellow crystalline powder
+95.0° - +105.0° (c=1, MeOH)
Store long-term at 2-8°C
DMSO: =8 mg/mL at 60 °C
Receptor antagonist (LTRA)
REVIEW Montelukast selectively antagonizes leukotriene D4 (LTD4) at the cysteinyl leukotriene receptor, CysLT1, in the human airway. Montelukast inhibits the actions of LTD4 at the CysLT1 receptor, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus.
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