[1508-75-4] Tropicamide AKSci E107
 
 
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  E107    AKSci Reference Standard
Tropicamide
, 98% (HPLC)
 
N-Ethyl-2-phenyl-N-(4-pyridylmethyl)hydracrylamide




IDENTITY
CAS Number:[1508-75-4]
MDL Number:MFCD00058580
MF:C17H20N2O2
MW:284.35
EINECS:216-140-2
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Available Spectra:LCMS, HPLC
Physical Form:White crystalline powder
Melting Point:96-97°C
Long-Term Storage:Store at room temperature
UN #:Not ha

BIOLOGICAL INFO
Application(s):Anticholinergic and a muscarinic receptor subtype M4-preferring antagonist

REVIEW

 Tropicamide binds to and blocks the receptors in the muscles of the eye (muscarinic receptor M4). Tropicamide acts by blocking the responses of the iris sphincter muscle to the iris and ciliary muscles to cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle.

REFERENCES
[1]Manny RE, Hussein M, Scheiman M, Kurtz D, Niemann K, Zinzer K (July 2001). Tropicamide (1%): an effective cycloplegic agent for myopic children. Investigative Ophthalmology & Visual Science 42 (8): 1728-35. PMID 11431435.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H302+H312+H332; H315; H317; H319; H335

Precautionary Statements
P261; P264; P270; P271; P272; P280; P301+P312; P302+P352; P304+P340; P305+P351+P338; P312; P322; P330; P333+P313; P337+P313; P362; P403+P233; P405; P501


Current as of February 26, 2017

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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CATEGORIES

 APIs and Bioactives > Ophthalmology, AChR Antagonists


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