N,N-Dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine benzoate salt
IDENTITY
CAS Number:
145202-66-0
MDL Number:
MFCD00866224
MF:
C22H25N5O2
MW:
391.47
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:
98% (HPLC), powder
Physical Form (at 20°C):
Solid
Melting Point:
175-184°C
Long-Term Storage:
Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material
BIOLOGICAL INFO
Solubility:
DMSO: 20mg/mL; H2O: 46mg/mL; EtOH: <1mg/mL
Application(s):
5-HT1 agonist
Form:
Benzoate salt
REVIEW A serotonin 5-HT1 agonist triptan drug for the treatment of migraine headaches.
REFERENCES
[1]
Ho TW, Pearlman E, Lewis D, Hämäläinen M, Connor K, Michelson D, Zhang Y, Assaid C, Mozley LH, Strickler N, Bachman R, Mahoney E, Lines C, Hewitt DJ; Rizatriptan Protocol 082 Pediatric Migraine Study Group (2012). Efficacy and tolerability of rizatriptan in pediatric migraineurs: results from a randomized, double-blind, placebo-controlled trial using a novel adaptive enrichment design. Cephalalgia. 32(10):750-65. PMID 22711898.
[2]
Müller T, Lohse L (2011). Efficacy of parecoxib, sumatriptan, and rizatriptan in the treatment of acute migraine attacks. Clin Neuropharmacol. 34(6):206-9. PMID 21996647.
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