541-15-1 L-Carnitine AKSci D688
 
 
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  D688    AKSci Bulk Reagent
L-Carnitine, 98% (HPLC)
 
Levocarnitine
Carnitor
(-)-(R)-3-Hydroxy-4-(trimethylammonio)butyrate
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IDENTITY
CAS Number:541-15-1
MDL Number:MFCD00038747
MF:C7H15NO3
MW:161.2
EINECS:208-768-0
BRN:4292315
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Spectra:NMR, LCMS, HPLC, Polarimetry
Physical Form:White crystalline powder
Melting Point:197-212°C
Optical Rotation:-31° (c=1, H2O)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:Water: 100g/L (20°C)

REVIEW
 Levocarnitine can be synthesised within the body from the amino acids lysine or methionine. Vitamin C (ascorbic acid) is essential to the synthesis of carnitine. Levocarnitine is a carrier molecule in the transport of long chain fatty acids across the inner mitochondrial membrane. It also exports acyl groups from subcellular organelles and from cells to urine before they accumulate to toxic concentrations. Only the L isomer of carnitine (sometimes called vitamin BT) affects lipid metabolism. Levocarnitine is handled by several proteins in different pathways including carnitine transporters, carnitine translocases, carnitine acetyltransferases and carnitine palmitoyltransferases.

REFERENCES
[1]Olpin SE: Fatty acid oxidation defects as a cause of neuromyopathic disease in infants and adults. Clin Lab. 2005;51(5-6):289-306.
[2] Steiber A, Kerner J, Hoppel CL: Carnitine: a nutritional, biosynthetic, and functional perspective. Mol Aspects Med. 2004 Oct-Dec;25(5-6):455-73.
[3] Bose, D. Subhas; Synthesis 2006, (11), P1863-1867

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of September 20, 2021


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CATEGORIES
 Amino Acids > Unnatural Amino Acids


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