60-32-2 6-Aminocaproic acid AKSci D007
 
 
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  D007    AKSci Bulk Reagent
6-Aminocaproic acid
, 99% (HPLC)
 
Aminocaproic acid
Amicar
6-aminohexanoic acid
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IDENTITY
CAS Number:60-32-2
MDL Number:MFCD00008238
MF:C6H13NO2
MW:131.17
EINECS:200-469-3
BRN:906872
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:99% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:204-212°C
Long-Term Storage:Store long-term at 2-8°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO: 6mg/mL; H2O: 26mg/mL; EtOH: 1mg/mL
Application(s):Antifibrinolytic Agent; Proteolytic Enzyme Inhibitor
Form:Free Base

REVIEW

 Aminocaproic acid is used to treat excessive postoperative bleeding. It is a derivative and analogue of the amino acid lysine, which makes it an effective inhibitor for enzymes that bind that particular residue. Such enzymes include proteolytic enzymes like plasmin, the enzyme responsible for fibrinolysis.

REFERENCES
[1]Thondorf I, Voigt V, Schäfer S, Gebauer S, Zebisch K, Laug L, Brandsch M (2011). Three-dimensional quantitative structure-activity relationship analyses of substrates of the human proton-coupled amino acid transporter 1 (hPAT1). Bioorg Med Chem. 19(21):6409-18. PMID 21955456.
[2] Banerjee A, Stoica C, Walia A (2011). Acute hyperkalemia as a complication of intravenous therapy with epsilon-aminocaproic acid. J Clin Anesth. 23(7):565-8. PMID 22050802.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P280; P261; P271; P302+P352; P332+P313; P362; P305+P351+P338; P337+P313; P403+P233; P405; P503; P501


Current as of December 6, 2022


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CATEGORIES

 Amino Acids > Unnatural Amino Acids
 APIs and Bioactives > Antihemorrhagics
 APIs and Bioactives > Antihemorrhagics


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