52214-84-3 Ciprofibrate AKSci C562
 
 
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  C562    
Ciprofibrate
, 98% (HPLC)
 
2-[p-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid




IDENTITY
CAS Number:52214-84-3
MDL Number:MFCD00467135
MF:C13H14Cl2O3
MW:289.15
EINECS:257-744-6
SPECIFICATIONS & PROPERTIES
Purity:98% (HPLC)
Spectra:LCMS, FT-IR, HPLC
Physical Form:White to light yellow powder
Melting Point:114-119°C
Long-Term Storage:Store long-term at 2-8°C

BIOLOGICAL INFO
Solubility:DMSO
Application(s):Peroxisome proliferator-activated receptor agonist

REVIEW

 Ciprofibrate is a fibrate drug used to lower levels of cholesterol and other lipids in the blood. It stimulates the action of lipoprotein and hepatic lipases in the blood. It also decreases the production of triglycerides by the liver. As a result of both these actions, it lowers the levels of blood lipids.

REFERENCES
[1]Phillips, Donald Kenney 2-[(2,2-Dihalocyclopropyl)phenoxy]-2-methylpropionic acids and their esters Ger. Offen. (1974), DE 2343606 A1 19740307.
[2] Thorpe, John Graham; Peel, Richard Halocyclopropyl-substituted phenoxyalkanoic acids and esters Eur. Pat. Appl. (1985), EP 142979 A2 19850529.
[3] Villani, Flavio; Nardi, Antonio; Salvi, Annibale; Falabella, Giovanna Preparation of 2-[4-(2,2-dihalocyclopropyl)phenoxy]-alkanoic acids and their esters via the Baeyer-Villiger reaction PCT Int. Appl. (2002), WO 2002090307 A1 20021114.
[4] Betteridge DJ.Ciprofibrate--a profile. Postgrad Med J. 1993;69 Suppl 1:S42-7; discussion S47-9.

GHS

Pictograms

Signal Word
Danger

Hazard Statements
H350

Precautionary Statements
P201; P202; P281; P308+P313; P405; P501


Current as of October 20, 2019


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For research use only. Not for diagnostic or therapeutic use.
Not for human use.


CATEGORIES

 APIs and Bioactives > Hypercholesterolemia, Fibrates


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