97744-44-0 Dibenzylfluorescein (DBF) AKSci AMTGC248
 
 
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  AMTGC248    
Dibenzylfluorescein (DBF)
, 97%
 
Benzyl 2-(6-(benzyloxy)-3-oxo-3H-xanthen-9-yl)benzoate




IDENTITY
CAS Number:97744-44-0
MDL Number:MFCD13184323
MF:C34H24O5
MW:512.55
SPECIFICATIONS & PROPERTIES
Purity:97%
Physical Form:Solid
Long-Term Storage:Store at room temperature
Note:Product of Advanced Molecular Technologies Pty Ltd. www.amtechpl.com

REVIEW

 DBF is dealkylated by cytochromes P450 (especially CYP2C8, CYP2C9, CYP2C19, and CYP3A) to form a fluorescein ester. Dibenzylfluorescein was reported to be suitable for in vitro assessment of the initial screening of CYP3A4-mediated drug interactions. The fluorescent fluorescein product can be quantitated after the addition of base, which hydrolyzes the ester and increases the pH for optimal fluorescein fluorescence detection.

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of July 7, 2020


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CATEGORIES

 Molecular Fluorophores & Dyes