97744-44-0 Dibenzylfluorescein (DBF) AKSci AMTGC248
 
 
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  AMTGC248    
Dibenzylfluorescein (DBF), 95%
 
Benzyl 2-(6-(benzyloxy)-3-oxo-3H-xanthen-9-yl)benzoate, NSC 645658
IDENTITY
CAS Number:97744-44-0
MDL Number:MFCD13184323
MF:C34H24O5
MW:512.55
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95%
Physical Form (at 20°C):Solid
Long-Term Storage:Store long-term in a cool, dry place
Note:Product of Advanced Molecular Technologies Pty Ltd. www.amtechpl.com
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 DBF is dealkylated by cytochromes P450 (especially CYP2C8, CYP2C9, CYP2C19, and CYP3A) to form a fluorescein ester. Dibenzylfluorescein was reported to be suitable for in vitro assessment of the initial screening of CYP3A4-mediated drug interactions. The fluorescent fluorescein product can be quantitated after the addition of base, which hydrolyzes the ester and increases the pH for optimal fluorescein fluorescence detection.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of September 19, 2024


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CATEGORIES
 Molecular Fluorophores & Dyes