161814-49-9 Amprenavir AKSci A899
 
 
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  A899    
Amprenavir
, 98% (HPLC)
 
Agenerase
Prozei
Vertex
more..




IDENTITY
CAS Number:161814-49-9
MDL Number:MFCD00934214
MF:C25H35N3O6S
MW:505.63
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:98% (HPLC)
Physical Form (at 20°C):Solid
Melting Point:70-77°C
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

BIOLOGICAL INFO
Solubility:DMSO
Application(s):HIV protease

REVIEW

 Amprenavir (Agenerase) is an an oral, non-peptidic peptidomimemtic viral protease inhibitor with specificity for the HIV protease enzyme, developed by Vertex Pharmaceuticals. The resistance profile of amprenavir appears to differ from that of other protease inhibitors such as saquinavir and indinavir.

REFERENCES
[1]C Arvieux, O Tribut, Amprenavir or fosamprenavir plus ritonavir in HIV infection: pharmacology, efficacy and tolerability profile, Drugs (2005), 65(5), 633-659.
[2] BM Sadler, DS Stein, Clinical pharmacology and pharmacokinetics of amprenavir, Annals of Pharmacotherapy (2002), 36(1), 102-118.
[3] S Noble, KL Goa, Amprenavir: A review of its clinical potential in patients with HIV infection, Drugs (2000), 60(6), 1383-1410.
[4] HB Fung, HL Kirschenbaum, R Hameed, Amprenavir: a new human immunodeficiency virus type 1 protease inhibitor, Clinical Therapeutics (2000), 22(5), 549-572

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of January 13, 2025


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