REVIEW Tilmicosin is a semisynthetic macrolide antibiotic prepared by chemical modification of desmycosil. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica, Tilmicosin has also been shown to have anti-inflammatory properties. It is structurally related to tylosin.
Ose EE. In vitro antibacterial properties of EL-870, a new semi-synthetic macrolide antibiotic. J Antibiot (Tokyo). 1987 Feb;40(2):190-4.
Schumann FJ, Janzen ED, McKinnon JJ. Prophylactic tilmicosin medication of feedlot calves at arrival. Can Vet J. 1990 Apr;31(4):285-8.
Mee JF, O'Farrell K. Tilmicosin and calf pneumonia. Vet Rec. 1991 May 11;128(19):460.
Debono, M., et al.: J. Antibiot., 42, 1253 (1989).