108050-54-0 Tilmicosin, mixture of isomers AKSci A574
 
 
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  A574    AKSci Reference Standard
Tilmicosin, mixture of isomers
, 95% (HPLC)
 
20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin, Antibiotic EL 870
EL 870
LY 177370
more..




IDENTITY
CAS Number:108050-54-0
MDL Number:MFCD00864842
MF:C46H80N2O13
MW:869.13
SPECIFICATIONS & PROPERTIES
Purity:95% (HPLC)
Spectra:FT-IR, LCMS, HPLC
Physical Form:White or beige powder
Optical Rotation:+12.75° (c=0.01, CHCl3)
Long-Term Storage:Store long-term at -20°C

REVIEW

 Tilmicosin is a semisynthetic macrolide antibiotic prepared by chemical modification of desmycosil. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica, Tilmicosin has also been shown to have anti-inflammatory properties. It is structurally related to tylosin.

REFERENCES
[1]Ose EE. In vitro antibacterial properties of EL-870, a new semi-synthetic macrolide antibiotic. J Antibiot (Tokyo). 1987 Feb;40(2):190-4.
[2] Schumann FJ, Janzen ED, McKinnon JJ. Prophylactic tilmicosin medication of feedlot calves at arrival. Can Vet J. 1990 Apr;31(4):285-8.
[3] Mee JF, O'Farrell K. Tilmicosin and calf pneumonia. Vet Rec. 1991 May 11;128(19):460.
[4] Debono, M., et al.: J. Antibiot., 42, 1253 (1989).

GHS

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501


Current as of August 21, 2019

AKSci Reference Standards are high-purity, low-impurity compounds suitable for use as standards.


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For research use only. Not for diagnostic or therapeutic use.
Not for human use.


CATEGORIES

 APIs and Bioactives > Antibacterials, Macrolides


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