108050-54-0 Tilmicosin, mixture of isomers AKSci A574
 
 
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  A574    AKSci Bulk Reagent
Tilmicosin, mixture of isomers, 95% (HPLC)
 
20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin, Antibiotic EL 870
EL 870
LY 177370
more..
IDENTITY
CAS Number:108050-54-0
MDL Number:MFCD00864842
MF:C46H80N2O13
MW:869.13
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:95% (HPLC)
Physical Form (at 20°C):Solid
Optical Rotation:+12.75° (c=0.01, CHCl3)
Long-Term Storage:Store long-term at -20°C
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 Tilmicosin is a semisynthetic macrolide antibiotic prepared by chemical modification of desmycosil. It is used in veterinary medicine for the treatment of bovine respiratory disease and ovine respiratory disease associated with Mannheimia (Pasteurella) haemolytica, Tilmicosin has also been shown to have anti-inflammatory properties. It is structurally related to tylosin.

REFERENCES
[1]Ose EE. In vitro antibacterial properties of EL-870, a new semi-synthetic macrolide antibiotic. J Antibiot (Tokyo). 1987 Feb;40(2):190-4.
[2] Schumann FJ, Janzen ED, McKinnon JJ. Prophylactic tilmicosin medication of feedlot calves at arrival. Can Vet J. 1990 Apr;31(4):285-8.
[3] Mee JF, O'Farrell K. Tilmicosin and calf pneumonia. Vet Rec. 1991 May 11;128(19):460.
[4] Debono, M., et al.: J. Antibiot., 42, 1253 (1989).

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of November 21, 2024


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CATEGORIES
 APIs and Bioactives > Antibacterials, Macrolides


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