H500 2-Methylnaphthoquinone - AK Scientific
 
 
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  Catalog ID # H500
2-Methylnaphthoquinone
, 97% (HPLC)
 
Menadione




IDENTITY
CAS Registry #:[58-27-5]
MDL Number:MFCD00001681
MF:C11H8O2
MW:172.18
EINECS:200-372-6
BRN:1908453
SPECIFICATIONS & PROPERTIES
Purity:97% (HPLC)
Physical Form:Yellow to yellow-green powder
Melting Point:104-108°C
Shipping:Not Regulated for Shipping.

REVIEW

 2-Methylnaphthoquinone is a synthetic chemical compound sometimes used as a nutritional supplement because of its vitamin K activity. It is an analog of 1,4-naphthoquinone with a methyl group in the 2-position, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo. 2-Methylnaphthoquinone is used in the treatment of Hypoprothrombinemia outside of the United States.

REFERENCES
[1]Kidd Parris M. Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. Alternative medicine review: a Journal of Clinical Therapeutic (2010) 15(3): 199-222.
[2] Kumagai, Yoshito; Shinkai, Yasuhiro; Miura, Takashi; Cho, Arthur K. The chemical biology of naphthoquinones and its environmental implications. Annual Review of Pharmacology and Toxicology. (2012) 52: 221-247.
[3] Lovern, Douglas; Marbois, Beth. Does menaquinone participate in brain astrocyte electron transport? Medical Hypotheses. (2013) 81(4): 587-591.
[4] Azizov, U. M.; Leont'eva, L. I.Methods for preparing 2-methyl-1,4-naphthoquinone (a review) Khimiko-Farmatsevticheskii Zhurnal (1989), 23(12), 1488-93.

Risk Description(s)
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.



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RELATED PRODUCTS
H5002-Methylnaphthoquinone
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CURRENT AS OF: April 18, 2015
Availability
1. In Stock: Order today by 4 PM PT and ships today from San Francisco, CA, USA
2. Backordered: Please contact us for availability.
3. If Bulk (kg) is Backordered, sizes less than 1kg may be available.
4. All prices FOB San Francisco, CA, USA
HazMat
HazMat shipping information is based on IATA/DOT regulations. For reference only.
1. Not Required: Not regulated by IATA/DOT. Normal shipping for Ground and Express.
2. Required for Express: HazMat shipping via Express. Normal shipping for continental Ground.

SDS

 H500_SDS.pdf

CATEGORIES

 APIs and Bioactives > Vitamins

USEFUL LINKS

  PubChem