H500 2-Methylnaphthoquinone - AK Scientific
 
 
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  Catalog ID # H500
2-Methylnaphthoquinone
, 98% (GC)
 
Menadione




IDENTITY
CAS Registry #:[58-27-5]
MDL Number:MFCD00001681
MF:C11H8O2
MW:172.18
EINECS:200-372-6
BRN:1908453
SPECIFICATIONS & PROPERTIES
Purity:98% (GC)
Available Spectra:NMR, GCMS, GC
Physical Form:Yellow to yellow-green powder
Melting Point:104-108°C
Long-Term Storage:Store at room temperature
Shipping:Not Regulated for Shipping

REVIEW

 2-Methylnaphthoquinone is a synthetic chemical compound sometimes used as a nutritional supplement because of its vitamin K activity. It is an analog of 1,4-naphthoquinone with a methyl group in the 2-position, but can be converted to active vitamin K2, menaquinone, after alkylation in vivo. 2-Methylnaphthoquinone is used in the treatment of Hypoprothrombinemia outside of the United States.

REFERENCES
[1]Kidd Parris M. Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy. Alternative medicine review: a Journal of Clinical Therapeutic (2010) 15(3): 199-222.
[2] Kumagai, Yoshito; Shinkai, Yasuhiro; Miura, Takashi; Cho, Arthur K. The chemical biology of naphthoquinones and its environmental implications. Annual Review of Pharmacology and Toxicology. (2012) 52: 221-247.
[3] Lovern, Douglas; Marbois, Beth. Does menaquinone participate in brain astrocyte electron transport? Medical Hypotheses. (2013) 81(4): 587-591.
[4] Azizov, U. M.; Leont'eva, L. I.Methods for preparing 2-methyl-1,4-naphthoquinone (a review) Khimiko-Farmatsevticheskii Zhurnal (1989), 23(12), 1488-93.

Risk Description(s)
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin

Safety Description(s)
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36:Wear suitable protective clothing.



Pricing

RELATED PRODUCTS
H5002-Methylnaphthoquinone
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CURRENT AS OF: August 27, 2016

Availability
1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

HazMat
HazMat shipping information is based on IATA/DOT regulations. All of the information is for reference only and subject to change without notice.

Quality
1. All products' quality is guaranteed.
2. Lot-specific spectra and CoA available on request.

Usage
AK Scientific products are intended for Research and Development usage only. The products are not to be used for other purposes, including, but not limited to, human or animal use, or as a component in, a food, drug, medical device (including in vitro diagnostic reagents), cosmetics and pesticides.

The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

AK Scientific is not an EPA registered pesticidal establishment. Our products are not intended for pesticidal applications.

SDS

 H500_SDS.pdf

CATEGORIES

 APIs and Bioactives > Vitamins

USEFUL LINKS

  PubChem