R787 4-Aza-5alpha-androstan-1-ene-3-one-17beta-carboxylic acid - AK Scientific
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  Catalog ID # R787
4-Aza-5alpha-androstan-1-ene-3-one-17beta-carboxylic acid
, 98% (HPLC)

CAS Registry #:[104239-97-6]
MDL Number:MFCD08063794
Purity:98% (HPLC)
Available Spectra:LCMS, HPLC
Physical Form:Off-white to yellow-brown powder
Melting Point:>250°C
Long-Term Storage:Store at room temperature
Shipping:Not Regulated for Shipping


 4-Aza-5alpha-androstan-1-ene-3-one-17beta-carboxylic acid or Dutasteride (trademark name Avodart, manufactured by GlaxoSmithKline) is a dual (type 1 and 2) 5-alpha reductase inhibitor that inhibits conversion of testosterone to dihydrotestosterone (DHT). It is used for benign prostatic hyperplasia and its chemopreventation, however increases the risk of erectile dysfunction and decrease sexual desire.

[1]Zhao, Shuang; Bioorganic & Medicinal Chemistry Letters 2011, V21(11), P3439-3442
[2] Satyanarayana, Komati; Organic Process Research & Development 2007, V11(5), P842-845
[3] Zhang, Kui-Ping; Journal of Chinese Pharmaceutical Sciences 2007, V16(3), P233-235
[4] Rasmusson, Gary H.; Reynolds, Glenn F.; Steinberg, Nathan G.; Walton, Edward; Patel, Gool F.; Liang, Tehming; Cascieri, Margaret A.; Cheung, Anne H.; Brooks, Jerry R.; Berman, Charles; Azasteroids: structure-activity relationships for inhibition of 5alpha-reductase and of androgen receptor binding. Journal of Medicinal Chemistry (1986), 29(11), 2298-315.

CURRENT AS OF: October 22, 2016

1. Backordered: Please contact us for availability.
2. All prices FOB San Francisco, USA

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The hazards associated with this chemical have not been fully evaluated. This chemical is to be used for research and development purposes only, under the supervision of a technically qualified individual.

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 APIs and Bioactives > Antiandrogens, Steroid Hormones


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