190786-44-8 Bepotastine besilate AKSci J91962
 
 
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  J91962    
Bepotastine besilate, 97%
 



IDENTITY
CAS Number:190786-44-8
MDL Number:MFCD01938491
MF:C27H31ClN2O6S
MW:547.06
SPECIFICATIONS & PROPERTIES
Min. Purity Spec:97%
Physical Form (at 20°C):Solid
Melting Point:162-164°C
Optical Rotation:+6° (c=5, MeOH)
Long-Term Storage:Store long-term in a cool, dry place
DOT/IATA TRANSPORT INFORMATION
Not hazardous material

REVIEW
 Bepotastine Beslilate (Bepreve) is a histamine H1 receptor anatagonist. Bepotastine Beslilate (Bepreve)also suppresses some allergic inflammatory processes such as allergic rhinitis, chronic urticaria or pruritus associated with skin conditions (eczema/dermatitis, prurigo or pruritus cutaneus).Bepotastine Beslilate (Bepreve) is useful for allergic conjunctivitis.

REFERENCES
[1]Williams JI, Kennedy KS, Gow JA, Torkildsen GL, Abelson MB, Gomes PJ, McNamara TR; Bepotastine Besilate Ophthalmic Solutions Study Group.Prolonged effectiveness of bepotastine besilate ophthalmic solution for the treatment of ocular symptoms of allergic conjunctivitis.J Ocul Pharmacol Ther. 2011 Aug;27(4):385-93. Epub 2011 Jun 7.
[2] Kawakami T, Kimura S, Haga T, Doi R, Kyoya M, Nakagawa K, Soma Y.Health-related quality of life assessed by the effect of bepotastine besilate in patients with pruritus: importance of emotions score in atopic dermatitis.J Dermatol. 2012 Jun;39(6):527-30.
[3] Meier EJ, Torkildsen GL, Gow JA, McNamara TR, Gomes PJ, Williams JI; for the Bepotastine Besilate Ophthalmic Solutions Study Group.Integrated phase III trials of bepotastine besilate ophthalmic solution 1.5% for ocular itching associated with allergic conjunctivitis.Allergy Asthma Proc. 2012 May;33(3):265-274.
[4] Cho KH, Choi HG.Development of novel bepotastine salicylate salt bioequivalent to the commercial bepotastine besilate in beagle dogs.Drug Dev Ind Pharm. 2012 Sep 10.

GLOBALLY HARMONIZED SYSTEM (GHS)

Pictograms

Signal Word
Warning

Hazard Statements
H315; H319; H335

Precautionary Statements
P261; P264; P271; P280; P302+P352; P304+P340; P305+P351+P338; P312; P321; P332+P313; P337+P313; P362; P403+P233; P405; P501

Current as of May 3, 2024


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⚠️
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CATEGORIES
 APIs and Bioactives > Antihistamines


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